Our weekly letter
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One clinical question, properly explained, in six minutes.
Why do we give adrenaline during cardiac arrest? Which rhythms should we shock? Why do we prescribe fluids the way we do?
Each six-minute letter traces a familiar part of clinical practice through its physiology, original evidence and medical history — so you understand not just what we do, but why.
Previous letters4
Why you should pay attention to the pulse waveform in asthma18 October 2026 · 5 min readGood morning — this week we have 20 new pages in bleep.guide, a new directory to store useful numbers at your hospital, and we're doing an acute…Meet the new bleep.guide4 October 2026 · 3 min readMorning —What is amiodarone actually doing after the third shock?6 September 2026 · 6 min read🫀 What amiodarone actually doing after the third shock — why do we give it acutely when it takes months to achieve steady-state?Why we give adrenaline during CPR30 August 2026 · 6 min read💉 Why we give adrenaline during CPR — and why it is not to restart the heart





